Ayunova Pharmaceutical LLP

Product Name

Mannitol Injection IP – 500 ml
(Osmotic Diuretic Intravenous Infusion)

Product Description

Mannitol Injection IP is a sterile, non-pyrogenic intravenous solution containing Mannitol, an osmotic diuretic used to reduce raised intracranial pressure, intraocular pressure, and to promote diuresis. It works by increasing plasma osmolarity, drawing water from tissues into the bloodstream, and enhancing renal excretion of water.

This infusion is widely used in neurosurgery, ophthalmology, emergency medicine, ICUs, and renal care units.

Composition

Each 100 ml contains:

• Mannitol IP – 20 g (20% w/v)

• Water for Injection IP – q.s.

(Each 500 ml contains 100 g of Mannitol)
(Strength may vary: 10% / 20% / as per label)

Uses / Indications Primary Indications

• Reduction of raised intracranial pressure (ICP)

• Reduction of intraocular pressure

Extended / Long Indications (IndiaMART Optimized)

• Cerebral edema associated with head injury or brain surgery

• Acute glaucoma and pre-operative ocular pressure reduction

• Promotion of diuresis in acute renal failure (oliguric phase)

• Prevention of renal failure in trauma, burns, or shock

• Management of drug and toxin poisoning (forced diuresis)

• Reduction of cerebral swelling during neurosurgical procedures

• Adjunct therapy in rhabdomyolysis

• Maintenance of urine output in critically ill patients

• Supportive therapy in severe edema conditions

Dosage & Administration

• Route: Intravenous infusion

• Dosage: As prescribed by physician based on clinical condition

• Administration: Slow IV infusion using sterile equipment

⚠ Warm solution if crystals are present before use
⚠ Monitor renal function, electrolytes, and fluid balance

Packaging Details

• 500 ml Glass / Plastic / Euro Head Bottle

• Leak-proof, tamper-evident packaging

• Hospital bulk and export-grade packing available

Storage Conditions

• Store below 30°C

• Protect from light

• Do not freeze

• Ensure solution is clear before use

Product Description

Mannitol 20% Sterile Solution is an osmotic diuretic used intravenously to reduce elevated intracranial and intraocular pressure and to promote diuresis. It is widely used in hospitals and critical care settings for the management of cerebral edema, acute renal failure, and glaucoma. The solution is sterile, non-pyrogenic, and intended for intravenous infusion only.

Composition

Each 100 ml contains:

• Mannitol IP – 20 g

• Water for Injection IP q.s.

Uses / Indications

Mannitol 20% Sterile Solution is indicated for:

• Reduction of increased intracranial pressure and cerebral edema

• Reduction of elevated intraocular pressure (before or after ophthalmic procedures)

• Promotion of diuresis in acute renal failure

• Prevention and treatment of acute kidney injury

• Forced diuresis in certain cases of drug intoxication

Dosage & Administration

• Dosage: As directed by the physician

• Route: Intravenous infusion only

• Warm the solution if crystallization occurs and ensure clarity before administration

Storage Instructions

• Store at room temperature (below 25°C)

• Protect from excessive cold as crystals may form

• Do not freeze

• Keep out of reach of children

Warnings & Precautions

• To be used under medical supervision only

• Contraindicated in patients with severe renal disease, pulmonary edema, or active intracranial bleeding

• Monitor fluid and electrolyte balance during therapy

• Do not use if solution is not clear

Packaging Details

• Available Pack Sizes: 100 ml / 200 ml / 300 ml (as applicable)

• Packaging Type: Glass / Plastic IV bottle

• Form: Ready-to-use sterile IV infusion

Product Name

HMG (Human Menopausal Gonadotropin) for Injection BP

Product Description

HMG for Injection BP is a purified gonadotropin preparation containing FSH (Follicle Stimulating Hormone) and LH (Luteinizing Hormone), derived from the urine of postmenopausal women. It is primarily used for stimulation of ovarian follicular development in women and assisted reproductive therapy (ART).

HMG mimics natural gonadotropins and is widely used in infertility management, ovulation induction, and in-vitro fertilization (IVF) protocols. It is administered intramuscularly or subcutaneously under specialist supervision.

Composition

Each vial contains:

• HMG BP (FSH + LH) – 75 IU / 150 IU / 225 IU per vial

• Excipients: q.s. sterile water for injection (lyophilized powder)

After reconstitution, it is ready for intramuscular (IM) or subcutaneous (SC) injection.

Major Indications / Uses Female Reproductive Health

• Induction of ovulation in women with anovulatory infertility

• Stimulation of follicular development in women undergoing ART (e.g., IVF, IUI)

• Luteal phase support in ovulation induction cycles

• Treatment of hypogonadotropic hypogonadism

Male Reproductive Health

• Stimulation of spermatogenesis in men with hypogonadotropic hypogonadism

Additional Uses

• Controlled ovarian hyperstimulation (COH) in assisted conception programs

• Combination protocols with HCG for final maturation and ovulation trigger

Dosage & Administration

• Route: Intramuscular (IM) or subcutaneous (SC) injection

• Dose (Women): Typically 75–225 IU/day, depending on ovarian response and protocol

• Dose (Men): Typically 75–150 IU 3 times per week, under endocrinologist supervision

• Monitoring: Follicular development, hormonal levels, and fertility treatment response

⚠ Administer only under supervision of a fertility specialist or endocrinologist

Packaging Details

• Available strengths: 75 IU, 150 IU, 225 IU vials

• Lyophilized powder for reconstitution

• Bulk and hospital packaging available

Storage Conditions

• Store 2–8°C (Refrigerated)

• Protect from light and moisture

• Do not freeze

• Keep out of reach of children

Liquid Rocuronium Bromide Injection – Hetroc Product Description

Hetroc (Liquid Rocuronium Bromide Injection) is a sterile, non-depolarizing neuromuscular blocking agent used to induce skeletal muscle relaxation during surgical procedures or mechanical ventilation. Rocuronium provides rapid onset muscle relaxation and is commonly used to facilitate endotracheal intubation and maintain anesthesia. The injection is intended for intravenous use under the supervision of trained healthcare professionals in hospitals and clinical settings.

Composition

• Active Ingredient:
  Rocuronium Bromide – [Specify mg per ml]

• Excipients:
  q.s.

• Dosage Form:
  Sterile liquid injection

Uses / Indications

Rocuronium Bromide Injection is indicated for:

• Muscle relaxation during general anesthesia

• Facilitation of endotracheal intubation

• Maintenance of skeletal muscle relaxation during mechanical ventilation

• As prescribed by an anesthesiologist or trained clinician

(Prescription medicine – hospital and clinical use only)

Dosage & Administration

• Administered intravenously by trained healthcare professionals

• Dosage depends on patient age, weight, and clinical condition

• Neuromuscular function and vital signs should be monitored during administration

Storage Instructions

• Store below 25°C

• Protect from light

• Keep the vial tightly closed

• Keep out of reach of children

Precautions & Warnings

• For prescription use only

• Use with caution in patients with hepatic, renal, or neuromuscular disorders

• Monitor respiratory and cardiovascular status during administration

• Not recommended during pregnancy unless clearly indicated

Packaging Details

• Vial containing [specify volume and strength]

• Supplied with protective outer carton

Quality Standards

• Manufactured in compliance with IP and GMP guidelines

• Tested for sterility, potency, and safety

Country of Origin

• India

Propofol Injection IP 500 mg / 50 ml Product Description

Propofol Injection IP 500 mg / 50 ml is a sterile intravenous anesthetic agent used for the induction and maintenance of general anesthesia and sedation. It provides rapid onset and quick recovery, making it suitable for surgical procedures, intensive care sedation, and outpatient anesthesia. The formulation is intended for intravenous administration under the supervision of trained healthcare professionals.

Composition

• Active Ingredient:
  Propofol – 500 mg / 50 ml (10 mg/ml)

• Excipients:
  Soybean oil, glycerol, egg lecithin, sodium hydroxide, water for injection

• Dosage Form:
  Sterile injectable emulsion

Uses / Indications

Propofol Injection is indicated for:

• Induction of general anesthesia

• Maintenance of anesthesia during surgical procedures

• Sedation of mechanically ventilated patients in intensive care units

• Procedural sedation in minor surgical or diagnostic procedures

(Prescription medicine – hospital and clinical use only)

Dosage & Administration

• Administered intravenously by trained healthcare professionals

• Dose depends on patient age, weight, clinical condition, and procedure

• Continuous monitoring of respiratory and cardiovascular status is required

• Not for intramuscular use

Storage Instructions

• Store below 25°C

• Protect from light and heat

• Keep the vial tightly closed

• Keep out of reach of children

Precautions & Warnings

• For prescription use only

• Use with caution in patients with cardiac, respiratory, or hepatic impairment

• Monitor vital signs continuously during administration

• Not recommended during pregnancy unless clearly indicated

Packaging Details

• 50 ml vial containing 500 mg Propofol

• Supplied with protective outer carton

Quality Standards

• Manufactured in compliance with IP and GMP guidelines

• Tested for sterility, potency, and safety

Country of Origin

• India

Jakura – Tofacitinib Tablets 5 mg Product Description

Jakura Tablets contain Tofacitinib 5 mg, a Janus kinase (JAK) inhibitor used in the treatment of autoimmune and inflammatory disorders. Tofacitinib works by suppressing immune system overactivity, thereby reducing inflammation, joint pain, swelling, and disease progression. This medicine is prescribed for patients with inadequate response to conventional therapies and must be used under medical supervision.

Composition

• Active Ingredient:
  Tofacitinib – 5 mg per tablet

• Excipients:
  q.s.

• Dosage Form:
  Film-coated tablet

• Pharmacopoeial Standard:
  IP

Uses / Indications

Jakura (Tofacitinib) Tablets are indicated for:

• Rheumatoid arthritis (moderate to severe)

• Psoriatic arthritis

• Ulcerative colitis

• Other autoimmune or inflammatory disorders as prescribed by a physician

(Prescription medicine – to be used under medical supervision)

Dosage & Administration

• Dosage as directed by the treating physician

• Taken orally with or without food

• Tablets should be swallowed whole with water

• Routine monitoring of blood counts and liver function is advised

Storage Instructions

• Store below 30°C

• Protect from moisture and sunlight

• Keep out of reach of children

Precautions & Warnings

• Prescription drug only

• Increased risk of infections; patient monitoring required

• Not recommended during pregnancy or breastfeeding unless prescribed

• Use cautiously in patients with liver, kidney, or cardiovascular conditions

Packaging Details

• Strip packing (as available)

• Suitable for hospital, pharmacy, and distributor supply

Quality Standards

• Manufactured in accordance with IP & GMP guidelines

• Quality tested for safety, purity, and efficacy

Country of Origin

• India

Lignocaine Adrenaline Injection IP – 30 ml Product Description

Lignocaine Adrenaline Injection IP is a sterile local anesthetic formulation containing Lignocaine Hydrochloride with Adrenaline. It is used to provide local and regional anesthesia during minor surgical, dental, and diagnostic procedures. The addition of adrenaline prolongs the duration of anesthesia and reduces systemic absorption by causing local vasoconstriction. This injection is intended for use by trained healthcare professionals in hospital and clinical settings.

Composition

• Active Ingredients:

  • Lignocaine Hydrochloride IP – 2% w/v (20 mg/ml)

  • Adrenaline (Epinephrine) IP – 1:200,000 or 1:100,000 (as applicable)

• Volume:
  30 ml vial

• Excipients:
  q.s.

• Dosage Form:
  Sterile injection

Uses / Indications

Lignocaine Adrenaline Injection is indicated for:

• Local and regional anesthesia

• Dental and minor surgical procedures

• Diagnostic and therapeutic interventions requiring local anesthesia

(Prescription medicine – hospital and clinical use only)

Dosage & Administration

• Administered via infiltration or nerve block techniques

• Dosage depends on procedure, site, and patient condition

• To be administered only by trained healthcare professionals

Storage Instructions

• Store below 25°C

• Protect from light

• Do not freeze

• Keep out of reach of children

Apritant – Fosaprepitant Injection 150 mg / Vial Product Description

Apritant Injection contains Fosaprepitant Dimeglumine 150 mg, a neurokinin-1 (NK1) receptor antagonist used for the prevention of acute and delayed nausea and vomiting associated with highly and moderately emetogenic cancer chemotherapy. Fosaprepitant is a prodrug of aprepitant and is administered intravenously for rapid and effective antiemetic control. This injection should be used under the supervision of a qualified healthcare professional.

Composition

• Active Ingredient:
  Fosaprepitant Dimeglumine – 150 mg per vial

• Excipients:
  q.s.

• Dosage Form:
  Lyophilized powder for intravenous infusion

Uses / Indications

Apritant Injection is indicated for:

• Prevention of chemotherapy-induced nausea and vomiting (CINV)

• Prevention of acute and delayed emesis associated with cancer chemotherapy

• As part of combination antiemetic therapy

(Prescription medicine – hospital and oncology use only)

Dosage & Administration

• Administered by intravenous infusion after reconstitution

• Dosage and infusion schedule as prescribed by the oncologist

• To be administered only by trained healthcare professionals

Storage Instructions

• Store below 25°C

• Protect from light

• Keep out of reach of children

• Use reconstituted solution as per prescribing information

Nilocap 150 – Nilotinib Capsules 150 mg Product Description

Nilocap 150 Capsules contain Nilotinib 150 mg, a selective tyrosine kinase inhibitor (TKI) used in the treatment of chronic myeloid leukemia (CML). Nilotinib works by inhibiting the BCR-ABL protein, preventing the proliferation of leukemic cells and helping to control disease progression. This medication should be used under strict medical supervision.

Composition

• Active Ingredient:
  Nilotinib – 150 mg per capsule

• Excipients:
  q.s.

• Dosage Form:
  Hard gelatin capsule

• Pharmacopoeial Standard:
  IP / USP

Uses / Indications

Nilocap 150 Capsules are indicated for:

• Chronic myeloid leukemia (CML) in Philadelphia chromosome-positive (Ph+) patients

• For newly diagnosed patients or those resistant/intolerant to prior therapies

• Use under the supervision of a hematologist or oncologist

(Prescription medicine – hospital and specialty use only)

Dosage & Administration

• Take orally as prescribed by the physician

• Capsules should be swallowed whole with water

• Usually taken on an empty stomach

• Regular monitoring of blood counts, liver function, and ECG recommended

Storage Instructions

• Store below 30°C

• Protect from moisture and sunlight

• Keep out of reach of children

MEPUP – Mephentermine Injection IP Product Description

MEPUP Injection contains Mephentermine Sulphate Injection IP, a sympathomimetic amine used for the treatment and prevention of hypotension, especially during spinal or general anesthesia. Mephentermine acts by increasing blood pressure through vasoconstriction and cardiac stimulation. It is commonly used in operating theatres, intensive care units, and emergency settings under medical supervision.

Composition

• Active Ingredient:
  Mephentermine Sulphate IP – 15 mg/ml (strength may vary as per pack)

• Excipients:
  q.s.

• Dosage Form:
  Sterile injection

• Route of Administration:
  Intravenous / Intramuscular

Uses / Indications

Mephentermine Injection IP is indicated for:

• Treatment and prevention of hypotension during spinal or general anesthesia

• Management of acute hypotensive states

• Emergency and perioperative blood pressure support

(Prescription medicine – hospital and anesthesia use only)

Dosage & Administration

• Administered by IV or IM injection

• Dosage and frequency as directed by the anesthesiologist or physician

• Continuous monitoring of blood pressure and heart rate is recommended

Storage Instructions

• Store below 25°C

• Protect from light

• Do not freeze

• Keep out of reach of children

MYCOTERO – Mycophenolate Mofetil Tablets IP 500 mg Product Description

MYCOTERO Tablets contain Mycophenolate Mofetil 500 mg, an immunosuppressive medication used primarily to prevent organ transplant rejection. It works by inhibiting inosine monophosphate dehydrogenase (IMPDH), suppressing lymphocyte proliferation and immune response. MYCOTERO is commonly prescribed as part of combination immunosuppressive therapy and must be used under strict medical supervision.

Composition

• Active Ingredient:
  Mycophenolate Mofetil IP – 500 mg per tablet

• Excipients:
  q.s.

• Dosage Form:
  Tablet

• Pharmacopoeial Standard:
  IP

Uses / Indications

MYCOTERO Mycophenolate Mofetil Tablets are indicated for:

• Prevention of organ transplant rejection (kidney, heart, liver)

• Management of certain autoimmune conditions as prescribed by a specialist

(Prescription medicine – hospital and transplant use only)

Dosage & Administration

• Taken orally as directed by the physician

• Tablets should be swallowed whole with water

• Usually administered in combination with other immunosuppressive agents

• Regular monitoring of blood counts and renal function is recommended

Storage Instructions

• Store below 25°C

• Protect from moisture and light

• Keep out of reach of children

Predniwik – Methylprednisolone Acetate Injection IP 40 mg Product Description

Predniwik Injection contains Methylprednisolone Acetate Injection IP 40 mg, a long-acting corticosteroid used for its potent anti-inflammatory and immunosuppressive effects. It is commonly prescribed for the treatment of allergic reactions, inflammatory disorders, autoimmune diseases, and certain musculoskeletal conditions. Predniwik Injection is intended for intramuscular or intra-articular administration under medical supervision.

Composition

• Active Ingredient:
  Methylprednisolone Acetate IP – 40 mg

• Excipients:
  q.s.

• Dosage Form:
  Sterile suspension for injection

• Route of Administration:
  Intramuscular / Intra-articular

Uses / Indications

Methylprednisolone Acetate Injection IP is indicated for:

• Treatment of severe allergic reactions

• Inflammatory and autoimmune disorders

• Rheumatic and musculoskeletal conditions

• Dermatological and respiratory inflammatory conditions

• Other conditions as prescribed by the physician

(Prescription medicine – use under medical supervision)

Dosage & Administration

• Administered by IM or intra-articular injection as directed by a healthcare professional

• Dosage depends on the severity of the condition and patient response

• Shake well before use (suspension)

Storage Instructions

• Store below 25°C

• Protect from light

• Do not freeze

• Keep out of reach of children

Sulfasalazine Gastro-resistant Tablets 500 mg Product Description

Sulfasalazine Gastro-resistant Tablets 500 mg are anti-inflammatory and immunomodulatory medications used primarily in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease, as well as rheumatoid arthritis. The gastro-resistant formulation ensures that the active ingredient is released in the intestine rather than the stomach, improving efficacy and reducing gastric irritation.

Composition

• Active Ingredient:
  Sulfasalazine – 500 mg per tablet

• Excipients:
  q.s.

• Dosage Form:
  Gastro-resistant tablet

• Pharmacopoeial Standard:
  IP / USP

Uses / Indications

Sulfasalazine 500 mg Tablets are indicated for:

• Ulcerative colitis

• Crohn’s disease

• Rheumatoid arthritis and other inflammatory disorders as prescribed by a physician

(Prescription medicine – hospital and pharmacy use only)

Dosage & Administration

• Take orally as directed by the physician

• Swallow tablets whole with water; do not crush or chew

• Dosage depends on patient age, weight, and clinical condition

• Regular monitoring of blood counts and liver function is recommended during prolonged therapy

Storage Instructions

• Store below 30°C

• Protect from moisture and direct sunlight

• Keep out of reach of children

Cerenia Injectable Solution is indicated for the prevention and treatment of acute vomiting in dogs and for the prevention of vomiting caused by emetogenic or chemotherapeutic agents. Cerenia Tablets are indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

 are a targeted cancer therapy used to treat Patnaik grade II or III, recurrent, non-resectable cutaneous mast cell tumors in dogs. It works by inhibiting tyrosine kinases to stop tumor growth and angiogenesis.

 Retatrutide 20mg/3ml is a prefilled, self-injecting pen containing a triple-agonist GIP/GLP-1/Glucagon hormone receptor medication designed for weight management and metabolic health. It acts by curbing appetite and increasing calorie burning, with clinical trials showing potential for significant body weight reduction.

Retatrutide 20mg Pen Injection is an experimental, once-weekly triple-agonist (GLP-1, GIP, GCG) medication primarily developed for chronic weight management in individuals with obesity or overweight, showing potential to help users lose over 20% of their body weight.

Synedica Retatrutide 40mg Prefilled Injectable Pen is a cutting-edge medication designed for weight management and metabolic health.

is a potent, irreversible MAOI antidepressant primarily used to treat major depressive disorder, particularly "atypical," "non-endogenous," or "neurotic" depression often characterized by mixed anxiety and phobic features

NAD+ 1000 mg prefilled pen injections are used for subcutaneous administration to boost nicotinamide adenine dinucleotide (NAD+) levels, aiming to enhance cellular energy, improve mental clarity, accelerate recovery from fatigue, and support anti-aging. 

Maball Rituximab Injection 500 mg Product Description

Maball Injection contains Rituximab 500 mg, a monoclonal antibody used in the treatment of certain cancers and autoimmune diseases. Rituximab targets CD20-positive B lymphocytes, leading to their depletion and helping control disease progression. Maball Rituximab Injection is widely used in oncology and immunology and should be administered under strict medical supervision in hospital settings.

Composition

• Active Ingredient:
  Rituximab – 500 mg per vial

• Excipients:
  q.s.

• Dosage Form:
  Sterile concentrate for intravenous infusion

Uses / Indications

Maball Rituximab Injection is indicated for:

• Non-Hodgkin’s lymphoma (CD20-positive)

• Chronic lymphocytic leukemia (CLL)

• Rheumatoid arthritis (with methotrexate)

• Other autoimmune disorders as prescribed by a physician

(Prescription medicine – hospital and clinical use only)

Dosage & Administration

• Administered as an intravenous infusion only

• Dosage and infusion schedule as directed by the oncologist or physician

• Premedication may be required to reduce infusion-related reactions

• To be administered by trained healthcare professionals

Storage Instructions

• Store at 2°C–8°C (refrigerated)

• Do not freeze

• Protect from light

• Keep out of reach of children

2% LOX Injection – Lignocaine Injection 30 ml Product Description

2% LOX Injection contains Lignocaine Hydrochloride 2%, a local anesthetic and antiarrhythmic agent widely used to produce local or regional anesthesia. It provides rapid onset of action and effective pain control during minor surgical, dental, and diagnostic procedures. This injection is intended for use by trained healthcare professionals in hospitals and clinical settings.

Composition

• Active Ingredient:
  Lignocaine Hydrochloride IP – 2% w/v

• Equivalent to:
  Lignocaine Hydrochloride – 20 mg/ml

• Volume:
  30 ml vial

• Excipients:
  q.s.

• Dosage Form:
  Sterile injection

Uses / Indications

2% LOX Injection is indicated for:

• Local and regional anesthesia

• Minor surgical and diagnostic procedures

• Dental procedures

• Management of ventricular arrhythmias (as prescribed)

(Prescription medicine – hospital and clinical use only)

Dosage & Administration

• Administered via infiltration, nerve block, or other regional techniques

• Dosage depends on procedure, site, and patient condition

• To be administered only by trained healthcare professionals

Storage Instructions

• Store below 25°C

• Protect from light

• Do not freeze

• Keep out of reach of children

The Alluvi Retatrutide 40mg Injection Pen is a prefilled pen designed to support weight loss in individuals struggling with obesity.

Androcur 50mg is used to lower sexual desire in cases of abnormal sexual behaviors. It is also used to treat prostate cancer that cannot be treated